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holy_calamity writes "Some grainy black and white movies are receiving rave reviews from scientists. They are taken by a new microscope which, thanks to a 'strobing' electron gun, can image movement at sub-nanometer scales. Until now, only still images that smeared out movement were possible at such scales. The press release notes, 'The researchers first blasted the sample with a pulse of heat. The heated carbon atoms began to vibrate in a random, nonsynchronized fashion. Over time, however, the oscillations of the individual atoms became synchronized as different modes of the material locked in phase, emerging to become a heartbeat-like "drumming."' Further details and a few animations are available at Caltech's site."pa href="http://science.slashdot.org/article.pl?sid=08/11/22/0351224amp;from=rss"img src="http://slashdot.org/slashdot-it.pl?from=rssamp;op=imageamp;style=h0amp;sid=08/11/22/0351224"/a/ppa href="http://science.slashdot.org/article.pl?sid=08/11/22/0351224amp;from=rss"Read more of this story/a at Slashdot./p pa href="http://feedads.googleadservices.com/~at/TtC2_lLiIAC_1wbUErC7uvc0TK8/a"img src="http://feedads.googleadservices.com/~at/TtC2_lLiIAC_1wbUErC7uvc0TK8/i" border="0" ismap="true"/img/a/pimg src="http://feedproxy.google.com/~r/Slashdot/slashdot/~4/OPopmlcikE0" height="1" width="1"/

Publication Date: 2008 Nov 20 PMID: 19020616br/Authors: Park, T. - Sidorov, V. A. - Ronning, F. - Zhu, J. X. - Tokiwa, Y. - Lee, H. - Bauer, E. D. - Movshovich, R. - Sarrao, J. L. - Thompson, J. D.br/Journal: Naturebr/br/Superconductivity without phonons has been proposed for strongly correlated electron materials that are tuned close to a zero-temperature magnetic instability of itinerant charge carriers. Near this boundary, quantum fluctuations of magnetic degrees of freedom assume the role of phonons in conventional superconductors, creating an attractive interaction that 'glues' electrons into superconducting pairs. Here we show that superconductivity can arise from a very different spectrum of fluctuations associated with a local (or Kondo-breakdown) quantum critical point that is revealed in isotropic scattering of charge carriers and a sublinear, temperature-dependent electrical resistivity. At this critical point, accessed by applying pressure to the strongly correlated, local-moment antiferromagnet CeRhIn(5), magnetic and charge fluctuations coexist and produce electronic scattering that is maximal at the optimal pressure for superconductivity. This previously unanticipated source of pairing glue opens possibilities for understanding and discovering new unconventional forms of superconductivity.br/br/post to: a href = http://www.citeulike.org/posturl?url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Fcmd%3DRetrieve%26db%3DPubMed%26dopt%3DAbstract%26list_uids%3D19020616title=Entrez+PubmedCiteULike/a

Publication Date: 2008 Nov 19 PMID: 19020041br/Authors: Godsave, S. F. - Wille, H. - Kujala, P. - Latawiec, D. - Dearmond, S. J. - Serban, A. - Prusiner, S. B. - Peters, P. J.br/Journal: J Neuroscibr/br/Prion diseases are caused by accumulation of an abnormally folded isoform (PrP(Sc)) of the cellular prion protein (PrP(C)). The subcellular distribution of PrP(Sc) and the site of its formation in brain are still unclear. We performed quantitative cryo-immunogold electron microscopy on hippocampal sections from mice infected with the Rocky Mountain Laboratory strain of prions. Two antibodies were used: R2, which recognizes both PrP(C) and PrP(Sc); and F4-31, which only detects PrP(C) in undenatured sections. At a late subclinical stage of prion infection, both PrP(C) and PrP(Sc) were detected principally on neuronal plasma membranes and on vesicles resembling early endocytic or recycling vesicles in the neuropil. The R2 labeling was approximately six times higher in the infected than the uninfected hippocampus and gold clusters were only evident in infected tissue. The biggest increase in labeling density (24-fold) was found on the early/recycling endosome-like vesicles of small-diameter neurites, suggesting these as possible sites of conversion. Trypsin digestion of infected hippocampal sections resulted in a reduction in R2 labeling of 85%, which suggests that a high proportion of PrP(Sc) may be oligomeric, protease-sensitive PrP(Sc).br/br/post to: a href = http://www.citeulike.org/posturl?url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Fcmd%3DRetrieve%26db%3DPubMed%26dopt%3DAbstract%26list_uids%3D19020041title=Entrez+PubmedCiteULike/a

At first glance, this leaf from Bird Electron doesn't seem like such a bad idea: Provide people with a small, unamplified, discreet speaker that can hook up to pretty much any MP3 player, wrap it in...

pimg src="http://cache.gawker.com/assets/images/gizmodo/2008/11/leaf.jpg" width="350" height="309" /At first glance, this leaf from Bird Electron doesn't seem like such a bad idea: Provide people with a small, unamplified, discreet speaker that can hook up to pretty much any MP3 player, wrap it in a cute little leafy shell and clip it to a keychain. But then, emplease/em, consider the uses. When can't you just give you friends an earbud to share a song? When you're 13, on a bus with five friends, all of whom are on a pretty hard Chingy kick. emThat's when./em Japan can keep this one. [a href="http://www.akihabaranews.com/en/news-17060-Cute+Leaf+leather+key+ring+with+integrated+speaker.html"Akihabara/a]/p br style="clear: both;"/ a href="http://www.pheedo.com/click.phdo?s=34a066df74625de9edeab9b15f70d8c8p=1"img alt="" style="border: 0;" border="0" src="http://www.pheedo.com/img.phdo?s=34a066df74625de9edeab9b15f70d8c8p=1"//a img src="http://www.pheedo.com/feeds/tracker.php?i=34a066df74625de9edeab9b15f70d8c8" style="display: none;" border="0" height="1" width="1" alt=""/div class="feedflare" a href="http://feeds.gawker.com/~f/gizmodo/full?a=hBg3cgfZ"img src="http://feedproxy.google.com/~f/gizmodo/full?d=120" border="0"/img/a a href="http://feeds.gawker.com/~f/gizmodo/full?a=stCssoPx"img src="http://feedproxy.google.com/~f/gizmodo/full?d=41" border="0"/img/a a href="http://feeds.gawker.com/~f/gizmodo/full?a=0zFeElKS"img src="http://feedproxy.google.com/~f/gizmodo/full?i=0zFeElKS" border="0"/img/a a href="http://feeds.gawker.com/~f/gizmodo/full?a=Bhwp4hOa"img src="http://feedproxy.google.com/~f/gizmodo/full?i=Bhwp4hOa" border="0"/img/a /divimg src="http://feedproxy.google.com/~r/gizmodo/full/~4/W6wNGPHmcJs" height="1" width="1"/

Publication Date: 2008 Nov 19 PMID: 19020030br/Authors: Ma, X. M. - Kiraly, D. D. - Gaier, E. D. - Wang, Y. - Kim, E. J. - Levine, E. S. - Eipper, B. A. - Mains, R. E.br/Journal: J Neuroscibr/br/Rho GTPases activated by GDP/GTP exchange factors (GEFs) play key roles in the developing and adult nervous system. Kalirin-7 (Kal7), the predominant adult splice form of the multifunctional Kalirin RhoGEF, includes a PDZ [postsynaptic density-95 (PSD-95)/Discs large (Dlg)/zona occludens-1 (ZO-1)] binding domain and localizes to the postsynaptic side of excitatory synapses. In vitro studies demonstrated that overexpression of Kal7 increased dendritic spine density, whereas reduced expression of endogenous Kal7 decreased spine density. To evaluate the role of Kal7 in vivo, mice lacking the terminal exon unique to Kal7 were created. Mice lacking both copies of the Kal7 exon (Kal7(KO)) grew and reproduced normally. Golgi impregnation and electron microscopy revealed decreased hippocampal spine density in Kal7(KO) mice. Behaviorally, Kal7(KO) mice showed decreased anxiety-like behavior in the elevated zero maze and impaired acquisition of a passive avoidance task, but normal behavior in open field, object recognition, and radial arm maze tasks. Kal7(KO) mice were deficient in hippocampal long-term potentiation. Western blot analysis confirmed the absence of Kal7 and revealed compensatory increases in larger Kalirin isoforms. PSDs purified from the cortices of Kal7(KO) mice showed a deficit in Cdk5, a kinase known to phosphorylate Kal7 and play an essential role in synaptic function. The early stages of excitatory synaptic development proceeded normally in cortical neurons prepared from Kal7(KO) mice, with decreased excitatory synapses apparent only after 21 d in vitro. Expression of exogenous Kal7 in Kal7(KO) neurons rescued this deficit. Kal7 plays an essential role in synaptic structure and function, affecting a subset of cognitive processes.br/br/post to: a href = http://www.citeulike.org/posturl?url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Fcmd%3DRetrieve%26db%3DPubMed%26dopt%3DAbstract%26list_uids%3D19020030title=Entrez+PubmedCiteULike/a

Le JEDEC (Joint Electron Device Engineering Council), l’organisme en charge de normaliser les standards utilisés dans les semi-conducteurs, vient d’annoncer son intention de standardiser les SSD d’ici à la fin de l’année prochaine. Pour ce faire...

divp style="text-align:justify" a href="http://www.akihabaranews.com/news-17060-Cute+Leaf+leather+key+ring+with+integrated+speaker.html"img src="http://www.akihabaranews.com/news_pics/17060/b.jpg" width="128" height="83" border="0" alt="Cute+Leaf+leather+key+ring+with+integrated+speaker" title="Cute+Leaf+leather+key+ring+with+integrated+speaker" align="left" hspace="5" vspace="5" //abr / The Japanese Store Bird Electron, has put on the market the EZ20YG, a leather shape leaf key ring which also includes a small speaker and audio jack which can be use with ANY DAP on the market. Small cute useless but who knows it may save you one day or another if you have an urgent needs share your tunes to friends.br / br / ...br /br / a href="http://www.akihabaranews.com/en/news-17060-Cute+Leaf+leather+key+ring+with+integrated+speaker.html#comments"Reader Comments/a/pbr clear="all" //div div id="partners_feeds" ul lia href="http://www.dannychoo.com" target="_blank"dannychoo.com/a - Your portal to Japan (a href="http://feeds.feedburner.com/dannychoo_com_main_article_feed_eng" target="_blank"Subscribe/a)/li lia href="http://www.japanprobe.com" target="_blank"Japan Probe/a - Japan news and entertainment (a href="http://feeds.feedburner.com/JapanProbe" target="_blank"Subscribe/a)/li lia href="http://www.kirainet.com" target="_blank"Kirainet.com/a - A geek in Japan (a href="http://feeds.feedburner.com/kirainet-english" target="_blank"Subscribe/a)/li /ul /div script src="http://feeds.feedburner.com/~s/Akihabaranews_en?i=http://www.akihabaranews.com" type="text/javascript" charset="utf-8"/script pa href="http://feeds.feedburner.com/~a/Akihabaranews_en?a=6YTyCO"img src="http://feeds.feedburner.com/~a/Akihabaranews_en?i=6YTyCO" border="0"/img/a/pdiv class="feedflare" a href="http://feeds.feedburner.com/~f/Akihabaranews_en?a=dRiXN"img src="http://feeds.feedburner.com/~f/Akihabaranews_en?i=dRiXN" border="0"/img/a a href="http://feeds.feedburner.com/~f/Akihabaranews_en?a=6rVAN"img src="http://feeds.feedburner.com/~f/Akihabaranews_en?i=6rVAN" border="0"/img/a a href="http://feeds.feedburner.com/~f/Akihabaranews_en?a=xle0n"img src="http://feeds.feedburner.com/~f/Akihabaranews_en?i=xle0n" border="0"/img/a a href="http://feeds.feedburner.com/~f/Akihabaranews_en?a=31tun"img src="http://feeds.feedburner.com/~f/Akihabaranews_en?i=31tun" border="0"/img/a a href="http://feeds.feedburner.com/~f/Akihabaranews_en?a=aF3Wn"img src="http://feeds.feedburner.com/~f/Akihabaranews_en?i=aF3Wn" border="0"/img/a a href="http://feeds.feedburner.com/~f/Akihabaranews_en?a=f6eUN"img src="http://feeds.feedburner.com/~f/Akihabaranews_en?i=f6eUN" border="0"/img/a a href="http://feeds.feedburner.com/~f/Akihabaranews_en?a=3TQuN"img src="http://feeds.feedburner.com/~f/Akihabaranews_en?i=3TQuN" border="0"/img/a a href="http://feeds.feedburner.com/~f/Akihabaranews_en?a=Qcp8N"img src="http://feeds.feedburner.com/~f/Akihabaranews_en?i=Qcp8N" border="0"/img/a /divimg src="http://feeds.feedburner.com/~r/Akihabaranews_en/~4/460384507" height="1" width="1"/

Motivation: It is a question of whether the supramolecular organization of the protein complex has an impact on its function, or not. In the case of the photosystem II (PSII), water splitting might be influenced by cooperation of the PSIIs. Since PSII is the source of the atmospheric oxygen and because better understanding of the water splitting may contribute to the effective use of water as an alternative energy source, possible cooperation should be analyzed and discussed.

Results: We suggest that the dimeric organization of the PSII induces cooperation in the water splitting. We show that the model of monomeric PSII is unable to produce the oxygen after the second short flash (associated with the double turnover of the PSII), in contrast to the experimental data and model of dimeric PSII with considered cooperation. On the basis of this fact and partially from the support from other studies, we concluded that the double turnover of the PSII induced by short flashes might be caused by the cooperation in the water splitting. We further discuss a possibility that the known pathway of the electron transport through the PSII might be incomplete and besides D1-Y161, other cofactor which is able to oxidize the special chlorophyll pair (P680) must be considered in the monomeric PSII to explain the oxygen production after the second short flash.

Availability: Commented SBML codes (.XML files) of the monomeric and dimeric PSII models will be available (at the time of publication) in the BioModels database (www.ebi.ac.uk/biomodels).

Contact: lazard@seznam.cz

Supplementary information: Supplementary data are available at Bioinformatics online.