img src="http://c.fsdn.com/fm/screenshots/59408_thumb.jpg" align="right" alt="Screenshot" hspace="10" vspace="10" JOpt.SDK is an automated vehicle routing and dispatching component for both Java/J2SE and .NET. It can solve Travelling Salesman Problems (TSP) and Capacitated Vehicle Routing Problems with Time Windows (CVRP,VRPTW). It offers route and transport optimisation with respect to various constraints such as time windows, load capacities, and prescribed itinerary. The component is based on genetic algorithms, and automatically determines an optimized allocation of vehicels to an arbitrary set of orders. hr / strongLicense:/strong Other/Proprietary License hr / strongChanges:/strongbr / The assisted mode has become the default case. The algorithm has been improved to address a broad range of problem types, and the optimization now always starts with a construction algorithm to create initial solutions. After that, the initial solution is subsequently improved by a second algorithm. Timewindow support has been added to the mixed fleet construction algorithm. pa href="http://feedads.googleadservices.com/~a/xnK6BKX8H4f9F7lmXPQ5EdOR0O0/a"img src="http://feedads.googleadservices.com/~a/xnK6BKX8H4f9F7lmXPQ5EdOR0O0/i" border="0" ismap="true"/img/a/pimg src="http://feedproxy.google.com/~r/freshmeat/feeds/fm-releases-global/~4/QxgtIfn_ydA" height="1" width="1"/

img src="http://c.fsdn.com/fm/screenshots/59408_thumb.jpg" align="right" alt="Screenshot" hspace="10" vspace="10" JOpt.SDK is an automated vehicle routing and dispatching component for both Java/J2SE and .NET. It can solve Travelling Salesman Problems (TSP) and Capacitated Vehicle Routing Problems with Time Windows (CVRP,VRPTW). It offers route and transport optimisation with respect to various constraints such as time windows, load capacities, and prescribed itinerary. The component is based on genetic algorithms, and automatically determines an optimized allocation of vehicels to an arbitrary set of orders. hr / strongLicense:/strong Other/Proprietary License hr / strongChanges:/strongbr / The assisted mode has become the default case. The algorithm has been improved to address a broad range of problem types, and the optimization now always starts with a construction algorithm to create initial solutions. After that, the initial solution is subsequently improved by a second algorithm. Timewindow support has been added to the mixed fleet construction algorithm. pa href="http://feedads.googleadservices.com/~a/Z3xLRaeokec2jkKeKI30LRlkvec/a"img src="http://feedads.googleadservices.com/~a/Z3xLRaeokec2jkKeKI30LRlkvec/i" border="0" ismap="true"/img/a/pimg src="http://feedproxy.google.com/~r/freshmeat/feeds/fm-releases-unix/~4/QxgtIfn_ydA" height="1" width="1"/

IceClean 3.0.8

IceClean is a powerful Finder and System Maintenance and Optimization Tool using ONLY built-in System Tasks to help your Mac stay healty and to keep it running smoothly. IceClean lets you execute the following tasks:

• System Maintenance Process
• System Cleanup
• Dashboard On/Off
• Three Spotlight features (Rebuild, Update, Optimize)
• Show Hidden FIles and Folders
• Finder Customization
• CD-DVD RW Quick Erase
• Force Empty Trashes and Securely Delete
• Lock your Screen

WHAT'S NEWVersion 3.0.8L

• Bug fixed
• Ready for 10.5.5

REQUIREMENTSMac OS X 10.5 or later.
DEVELOPERMacDentro.com
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Publication Date: 2008 Nov 27 PMID: 19038030br/Authors: Rocha, M. - Maia, P. - Mendes, R. - Pinto, J. P. - Ferreira, E. C. - Patil, K. - Nielsen, J. - Rocha, I.br/Journal: BMC Bioinformaticsbr/br/ABSTRACT: BACKGROUND: One of the greatest challenges in Metabolic Engineering is to identify a set of genetic manipulations that will result in a microbial strain that achieves a desired production goal. This challenge is due to, not only the inherent complexity of the metabolic and regulatory networks, but also to the lack of appropriate modelling and optimization tools. To this end, Evolutionary Algorithms (EAs) have been proposed for in silico metabolic engineering, for example, to identify sets of gene deletions towards maximization of a desired physiological objective function. In this approach, each mutant strain is evaluated by resorting to the simulation of its phenotype using the Flux-Balance Analysis (FBA) approach, together with the premise that microorganisms have maximized their growth along natural evolution. RESULTS: This work reports improved EAs, as well as novel Simulated Annealing (SA) algorithms to address the task of in silico metabolic engineering. Both approaches use a set based encoding scheme, together with appropriate operators to generate new solutions. The proposed algorithms use a variable size set-based representation, thereby allowing the automatic finding of the best number of gene deletions necessary for achieving a given productivity goal. The work presents extensive computational experiments, involving four case studies that consider the production of succinic and lactic acid as the targets, by using S. cerevisiae and E. coli as model organisms. The proposed algorithms are able to quickly reach good solutions regarding the production of the desired compounds and presenting low variability among the several runs. CONCLUSIONS: The results show that the proposed SA and EA both perform well in the optimization task. A comparison between them is favourable to the SA that seems to be more consistent in obtaining optimal solutions and displays a faster convergence to the solutions. In both cases, the use of variable sized representations allows the automatic discovery of the approximate number of gene deletions, without compromise in the optimality of the solutions.br/br/post to: a href = http://www.citeulike.org/posturl?url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Fcmd%3DRetrieve%26db%3DPubMed%26dopt%3DAbstract%26list_uids%3D19038030title=Entrez+PubmedCiteULike/a

Astro IIDC 4.01Astro IIDC works with a wide variety of low and high end, color or monochrome, 8 or 16 bit FireWire 400 or FireWire 800 cameras. It has a simple intuitive interface, can record movies, grab frames, grab averaged frames, grab sums of frames, has extensive Altivec / SSE3 optimization for real time processing for flat field, dark frame, image alignment and stacking, supports movie recording as fast as 240 frames per second to disk or as long as 1 hour per frame. The application utilizes our industrial strength Altivec / SSE3 optimized IIDC/DCAM Version 2.0 Framework to control the camera and extracts the raw bayer or monochrome images from the CCD.
WHAT'S NEWVersion 4.01 adds support for more Industrial cameras (i.e. AVT series, Bassler series, PixelLink, Sony, Unibrain series and others), adds MAP image stack generation, provides LRGB 16 bit individual color channel scaling, rotation and alignment, improved guiding, batch image processing, adds jpeg frame grabs, Apple script support for dark and flat frame automation, ability to save manually selected frames to a reference movie for repeat processing and general performance improvements.
REQUIREMENTSPowerPC G3, G4, G5 or MacIntel x86 Mac, OS X 10.3 or later, QuickTime 7 or higher, compatible FireWire camera (see web site for list)
DEVELOPERAupperle Services & Contracting
DOWNLOADS7492
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OnyX 2.0b1OnyX is a multifunction utility for Mac OS X (PowerPC and Intel). It allows you to verify the Startup Disk and the structure of its System files, to run misc tasks of system maintenance, to configure the hidden parameters of the Finder, Dock and of some of Apple's own applications, to delete caches, to remove a certain number of files and folders that may become cumbersome and more.
WHAT'S NEWVersion 2.0b1 (WARNING: Beta Version):

• Compiled with Xcode 3.1.2
• Deleting the applications Cache improved
• Deleting the Internet Cache improved
• Deleting the logs improved
• Confirm when closing multiple pages in safari
• Rebuilding the dyld's shared cache in the Automation panel
• Rebuilding the Mail's Envelope Index in the Automation panel
• Corrections in the translations
• Help improved
• Uninstaller updated

REQUIREMENTSMac OS X 10.5 or later.
DEVELOPERJoel Barriere
DOWNLOADS1162530
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