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Planet Ubuntu -
12 hours and 32 minutes ago
Thanks everyone for your questions to my previous post
on this subject. Now the results:
Everyone should install the Maemo Extras application catalog. Just unleash your phone by
installing this
repository.
After you are done installing this we go to the questions:
-
How is XMPP working out?
Good, so go doing your Facebooking or Jabbering everywhere. not to speak you Google Taking
-
The “Unlocks with ’sudo gainroot’” needs a
footnote:
* you need to enable the Maemo Extras application catalog (see above) and install
“rootsh”
* or, alternatively (and less conveniently), you need to enable R&D mode with the flasher
command-line tool on a PC, with the N900 connected over USB
-
Does the browser (fennec iirc?) include support for playing back Ogg video and
audio?
Ogg support can be added as an additional download. You do have the real Firefox now, or so
claims Nokia.
-
Telepathy supports skype? Haven’t heard of this, but it would be _really_
cool!
As written in my post “you have skype, but no skype app which is a
plus.” Yes telepathy handles skype as it handles any other protocol. MSN call
support is coming soon as well.
-
I’d really like to know how easy is to exploit all the cool features of N900 in a
self made program (with Maemo SDK or maybe QT 4.6). I mean, the N900 has a built in
camera, AGPS, accelerometer, FM-transmitter and so on... is it possibile to write a custom
program that uses one or more of these things? For example (it is really just a
weird example) if I want to take a photo with the camera each time the phone is
“shaked”, I could do it? If I want to save my GPS coordinates every 30
minutes in a text file, I could do it?
I guess I won’t be answering that question in this life time… If (and only if) I
ever try programming anything for maemo it will be in Python. I guess you can do pretty neat
things with QT + other libs as this
application shows. A detailed example of that app here
(De-Spotify related).
-
Test a/v calling on gtalk,jabber using telepathy works or not?
tried once and didn’t work. It could have been me or my other peer either being retarded
or just using Linux with the wrong sound config (experienced it before and it had nothing to do
with i.e. skype being wrong)
-
I have seen many people talking about unexpected errors, slow performance, etc.
What´s your overall experience?
I experience it as the easiest piece of tech I have ever had. It really is fast and gives me no
headaches.
-
Can you install .deb packages that are valid for a standard PC?
I guess I should elaborate in this question but I won’t. A deb package made in your PC
for the N900 architecture (armel) should work. But a standard x86 deb will not.
-
Can you install pidgin?
Why on earth would I want to do that? Telepathy is totally integrated in my contact list and
relevant applications… Pidgin in this context would be like having a skype application:
Just overhead! Think of this as a new approach at the way you
communicate, not a reproduction of an ineffective way of doing things.
-
I assume you mention OpenSSH from a client perspective. Can the N900 run the server
side? (not sure that makes sense, but I am curious)
It can and it rocks.
-
How many apps you feel it can run in parallel before it feels bloated?
I have my screen full of phone related apps, browser windows, multimedia stuff and random apps
(terminal, chess, camera) and it still does not feel bloated at all. I really mean it. I never
get irritated by this phone!
-
For how much you bought it and from where i am in Egypt and i want to buy one?
I did not buy it. I am just borrowing it (sort of) from a friend @ Nokia.
-
Its usefulness ...
It helps me being more effective when I am on the move and at the office. So it
really is useful. Not to speak of its awesomeness when enjoying my private time (i.e. camera
& video features)
-
I’ve ordered one that wont arrive for another month =( A few questions related to
barcodes. Can you take a picture of a barcode show it full screen and have scanners scan
it?
I read somewhere that you should be able to do so. Google it mate. I don’t need that and
really don’t have time to test that, sorry.
-
Is there a barcode scanner tool? Bonus for price comparison tools. Sometimes I’ll
be browsing used game stores and see a game fairly cheap and wonder whether I can get it
cheaper elsewhere.
Read  questions #14
-
If it isn’t too much trouble, I would like to know how well emacs works on the
device, I notice it doesn’t have a meta key.
Have given emacs way too many chances in other devices to make my life harder in this one. I am
really not the right person to ask as I do not feel emacs works at all anywhere (and the same
goes for vi/vim so do not hate the player, hate the game!
-
Web browsing while playing music (recorded or streaming); heard complaints that
playback may become choppy.
Works like a charm even under crappy wi-fi conditions.
-
Listening to music over BT stereo headphones and answering calls. Voice commands over
BT?
Lost my BT headset for a while ago and I really am not interested in buying a new one. If
someone has experience on this please answer in the comments.
-
Video calling. I know it’s not there yet in the integrated skype. But what about
Fring or Gtalk or Ytalk?
Tried skype and it worked like a charm. Do not use any of the others, sorry.
-
Voice announcements of incoming messages while listening to music over BT?
No idea. Read #18
-
Smoothness of video playback, whether recorded or streaming? (Again, heard complaints
of choppiness.)
I recorded the audio and video at a concert last weekend and it really worked well. It might
just be me and my lack of interest in video/audio quality in general.
-
Does it have what it takes to play h264 videos in mkv containers?
How can i test that?
-
Can you try different resolutions?
Why should I ever wish that? Drop me the command and I will run them
-
How is the sound quality on mp3, ogg and flac files?
Great. Nokia ere is king among mobile producers. Nothing can even compare to it, specialy when
playing from the speakers. When using headphones it just rocks!
-
How is the performance like for traditional desktop apps(amarok, akregator,
openoffice.org)?
I dreamed of installing the debian extra for maemo but never got far with it. Now I really do
not feel like blowing up my preciously nice working N900.
-
How is the performance of the ‘big’ desktop environments
(xfce, gnome, kde)
Hope I never have the time to go through that operation so I won’t have an
answer.
-
I’d like to see tested is how well this device works as a phone while all the
other crazy hacks are going on.
Works like a charm!
-
Test call quality, battery life, address book functionality, etc.
Cal quality is good. Battery life could be better (will last one day and two at the
most)Â Â and Address Book functionality is very nice specially if you
think about how well integrated everything is. I have had several smartphones over the years
and never seen anything like this.
-
I am curious how well the calendar works, and more importantly, how well it
synchronizes with Google Calendar.
I’ve heard it works like a charm although I do not use Gcalender so I
couldn’t tell.
-
Does it run X11?
I want to know but I don’t. It might do as I can connect to external machines with ssh -X
and get apps running on the N900 (such as eclipse)
-
In other words, is it pie-in-the-sky to expect to use it as a full-blown Linux box?
It ain’t a box, it’s a pone with debian. Isn’t that enough for you? It
certainly works for me!
Thanks for reading!


|
Guardian Unlimited -
14 hours and 27 minutes ago
Jim Carrey is a fraudster who falls for Ewan McGregor in a Texas jail. Peter Bradshaw enjoys an
intriguing, offbeat comedy
Jim Carrey's rubbery, hyperreal face achieves a sheen of panic and desperate neediness in this
stranger-than-fiction comedy drawn from real life. Steven Russell (Carrey) is a fraudster, a
hypnotically plausible fantasist, and a formerly married ex-cop who comes out as a gay man,
before finally getting sent to jail in Texas for insurance scams, and there finding the love of
his life. This is the shy, young innocent Phillip Morris, nicely played by Ewan McGregor, who,
like the rest of the world, trusts the exuberant and charming Steven implicitly. Morris himself
tells his own story in a seductive, honeyed voiceover, rather like Reese Witherspoon's narration
in Alexander Payne's Election.
Electrified by his new romance, Steven redoubles his fanatical determination to trick and
manipulate the world around him to get what he believes he wants: Phillip. When his own prison
term ends, Steven poses as a lawyer to get Phillip released on licence –
forging documents, faking voices on the phone, and maintaining a series of inspired bluffs
– and then constructs a massive, fraudulent career in both law and finance so
that they can live together in luxury as a super-rich gay couple. But it isn't long before the
police close in, and Steven has to demonstrate his almost superhuman talents for evading the law:
shabby deceptions theoretically consecrated to his love for his beloved Phillip, who hasn't
grasped how he has been made complicit and co-dependent in Steven's delusional career of lies.
This movie, from writer-directors Glenn Ficarra and John Requa – who wrote the
Billy Bob Thornton comedy Bad Santa – is intriguing, at least partly because
it is not immediately clear what it is centrally about. Steven's own lifelong identity crisis,
which may stem from the traumatic discovery of having been adopted, has a parallel in the film.
Is it about gay romance? Is it about a con man's criminal career? Are we, the audience, supposed
to trust Steven Russell, to take him at his own estimation of himself?
Not exactly, no. Even calling him a fraudster doesn't describe the character Carrey plays. His
compulsive lying is an addictive habit like kleptomania; it forces him to live in a growing web
of relationships based on bad faith, from which more scams will be needed to escape. Like many
liars, Steven has developed a lovably roguish personality as a cover for when he gets caught and
has to admit guilt, and as a face-saving device to allow his dupes to grimace and pretend they
sort of suspected as much. Steven is not a con man in the sense of a cool, rational grifter who
knows exactly what he is doing and why. He is in the grip of a compulsion, which distracts him
from a batsqueak of terror that he doesn't know what or who he is. Steven seizes messianically on
his gay identity and his gay love for Phillip Morris. The title of the film is a kind of personal
mission statement. But to the very end, this grand passion may not entirely explain his
behaviour.
Steven's soon-to-be-ex-wife Debbie, played by Leslie Mann, asks a doctor if Steven's "gay thing
and the stealing" are part of the same disorder. Steven's then-boyfriend Jimmy, played by Rodrigo
Santoro, is disgusted by this homophobic remark. And yet Debbie, in her blundering way, has come
close to something. It is not Steven's gayness that is of a piece with his stealing, but his
pretending to be straight, and then pretending that his embrace of a gay identity is the solution
to all his personal problems. What counts is the deception, and the way it melts into
self-deception.
With its chequered and meandering story-path, I Love You Phillip Morris reminded me surreally of
serial killer films like David Fincher's Zodiac, Cédric Kahn's Roberto Succo and Shohei
Imamura's Vengeance Is Mine – about criminals whose modus operandi and
repetitive patterns of behaviour look like a rationally pursued criminal "career"
– but it is a career that could digress or disappear at any moment.
Carrey and McGregor certainly succeed in making it all funny. Carrey's anti-hero is, after all, a
very clever man, who gets away with a lot of stuff because of a genuine mental ability, which he
unfortunately supplements with lies. (There's a nice montage sequence in which Steven tells a
"lawyer" joke at the office, and then overhears dozens of people retelling that same joke badly,
revealing their various crass prejudices.)
And there is something funny and touching about this anarchic, abortive love affair, a
chaotically doomed relationship that neither of the principals understand, and it is the very
muddled and messy quality of this relationship that announces that it is drawn from real life.
Steven's bluffs and blags are arguably just a crazily magnified version of the
fake-it-till-you-make-it routine that many entirely honest people find themselves needing to use.
Poor Steven does see himself as basically one of these decent, honest types. "Sometimes you've
got to shave a little off the puzzle-piece to make it fit," he muses. The puzzle fits together
very entertainingly here.
Rating: 4/5
Peter Bradshawguardian.co.uk © Guardian News & Media Limited 2010 | Use
of this content is subject to our Terms & Conditions | More Feeds

|
GameSetWatch -
15 hours and 27 minutes ago
[Finishing up our GDC written coverage, we were going to pick just one lecture,
but we decided to just go with all of the major ones, as well as the big announcements - lots of
neat stuff to check through here.]
With Game Developers Conference 2010 now at an end, we've rounded up the top announcements, from
Sony Move through OnLive's release specifics, and write-ups of the biggest talks into one handy
news story.
The official GDC 2010 page on Gamasutra has more
than 100 news stories on one of the biggest events of the gaming year, but we're now highlighting
the biggest product-related announcements of the show.
This will be followed by our pick of the top ten most intriguing write-ups from the more than 450
sessions on display at this year's GDC in San Francisco - created by the UBM Techweb Game
Network, as is this website.
Here are some of the top announcements and write-ups from last week's show:
The Announcements
GDC: Sony's Motion
Controller Is 'PlayStation Move'
"At GDC on Wednesday, Sony revealed more details about its PS3 motion controller, which isn't
called Arc or Gem, but 'PlayStation Move,' a product Sony says will bring on 'the next generation
of motion gaming.'"
GDC: OnLive Gets Launch
Date, Reveals Initial Publishers
"Cloud-based game streaming service OnLive has announced an official U.S. launch date of June 17,
2010, including games from Electronic Arts, Ubisoft, 2K Games, THQ and Warner Bros. Interactive
Entertainment."
GDC: Microsoft Announces
XNA Game Studio 4.0
"Microsoft has announced version 4.0 of its XNA Game Studio development package, which includes
support for its new Windows Phone 7 Series, as well as enhancing features for Xbox 360 and PC
game development."
GDC: InstantAction Reveals
Platform For Instantly Playing Large-Download Games
"InstantAction unveiled its platform allowing users to play full PC games in their browser as
they download titles, made possible with a delivery mechanism that CEO Louis Castle tells
Gamasutra is superior to OnLive."
Valve Confirms Mac Versions
Of Steam, Valve Games
"Valve will release its Steam digital distribution service for Mac along with Mac-native versions
of its own games, the company confirmed today, calling the Mac a 'tier-1 platform.'"
Other notable GDC-timed announcements include: Bigpoint Announces Battlestar MMO,
Unity Partnership, San Francisco Office; Unity Announces 3.0 Platform,
Support For PS3, iPad, And Android; Palm to Debut webOS Plug-in
Development Kit at GDC 2010; MySpace Launches New Games
Experience, Tools.
The Top Lectures
GDC: Will Wright Peels Back
Layers Of Entertainment, Games
"Will Wright (The Sims, SimCity) explained how 'perspectives are more valuable than solutions' in
a fascinating talk during the closing hours of the Game Developers Conference 2010 on Saturday."
GDC: Jenova Chen's
HeavenVille Wins Game Design Challenge
"HeavenVille, Jenova Chen (Flower), took this year's top prize at the GDC Game Design Challenge,
which also featured games by designers Kim Swift, Heather Kelley, and Erin Robinson."
GDC: Sid Meier's Lessons On
Gamer Psychology
"'Gameplay is a psychological experience,' according to legendary Civilization creator Sid Meier,
who gave tips on taking advantage of player psychology during his GDC keynote Friday."
GDC: Hecker's Nightmare
Scenario - A Future Of Rewarding Players For Dull Tasks
"It's possible that an over-reliance on metrics-driven design and extrinsic rewards for in-game
actions could lead to a future of 'designing shitty games that you have to pay people to play,'
warns independent developer Chris Hecker."
GDC: Blizzard's Core Game
Design Concepts
"Blizzard EVP of game design Rob Pardo shares Blizzard's core design concepts, offering examples
of places where the World of Warcraft developer succeeded and failed in creating compelling
multiplayer experiences."
GDC: Nintendo's Sakamoto's
Four Creative Tenets
"Nintendo's Yoshio Sakamoto explains the methodology that allows him to create two franchises as
polar-opposite as Metroid and Wario Ware -- and drops hints on Other M."
GDC: Peter Molyneux On
Simplifying And Enhancing Fable III
"Lionhead's Peter Molyneux talked about the 'angst' Lionhead went through on whether to de-RPG
Fable III -- and why and how the team went through that process, from a design perspective."
GDC: ThatGameCompany's
Santiago, Hunicke Talk Exploratory Development
"An exploratory development process can be a solution to the anxieties of game development, but
only if it's managed with confidence and honesty, say Thatgamecompany's Kellee Santiago and Robin
Hunicke."
GDC: Indie Keynote -
Championing Immediacy And Depth
"Tiger Style co-founder Randy Smith (Spider: The Secret of Bryce Manor) delivered the keynote of
the Indie Games Summit, encouraging indie developers to embrace a philosophy of immediacy and
depth to hasten their popular ascendancy."
GDC: 2D Boy's Carmel On A
New Alternative For Indies
"At the 2010 Independent Gaming Summit at GDC, 2D Boy's Ron Carmel talked about why traditional
publishing just doesn't work for indies -- and why the newly-unveiled Indie Fund hopes to offer
alternatives."
Other notable GDC 2010 lecture write-ups include: Facebook Keynote Discusses True
Multi-Platform Gaming; Taking Inspiration from EVE
Online's Espionage Metagame; Creating Deus Ex Human Revolution's
Cybernetic Renaissance; Refining The Real-Time Combat In
Mass Effect 2; EA's
Cousins Talks Social Gaming's Wal-Mart Parallel.


|
[ Blog des TIC ] de webtolosa.fr -
16 hours and 14 minutes ago
Plesk est une géniale interface de gestion de serveur, payante et éditée par
Parallels
Géniale ? oui, mais ... si grand est son soucis de sécurité qu'il n'y a pas
moyen de faire avaler aux navigateurs courants la mémorisation des identifiants
d'accès.
J'avoue que c'est assez pénible, ce d'autant que la durée de la
session est (très) limitée.
Maaaaaaaaaaais il y a un truc !
Disons le tout de suite : ce truc est totalement "unsafe", bref une vraie faille de
sécurité.
Cela dit... c'est quand même sympa à garder dans ses favoris.
Il suffit de garder en marque-pages l'URL suivante :
https://URL:8443/login_up.php3?login_name=admin&passwd=motdepasse
- URL : l'adresse de la page de connexion (ou l'IP du serveur)
- motdepasse = ... ben... le mot de passe lool
- Pour la variable "name", si vous ne l'avez pas modifié, c'est "admin". Sinon vous
personnalisez aussi.
C'est tout !
|
CiteULike: Borelli's watchlist -
19 hours and 20 minutes ago
J Exp Biol, Vol. 212, No. 17. (1 September 2009), pp. 2721-2729.
The compound eye of the bee is an array of photoreceptors, each at an angle to the next, and
therefore it catches an image of the outside world just as does the human eye, except that the
image is not inverted. Eye structure, however, tells us little about what the bee actually
abstracts from the panorama. Moreover, it is not sufficient to observe that bees recognise
patterns, because they may be responding to only small parts of them. The only way we can tell what
the bee actually detects is to train bees to come to simple patterns or distinguish between two
patterns and then present the trained bees with test patterns to see what they have learned. After
much training and numerous tests, it was possible to identify the parameters in the patterns that
the bees detected and remembered, to study the responses of the trained bees to unfamiliar patterns
and to infer the steps in the visual processing mechanism. We now have a simple mechanistic
explanation for many observations that for almost a century have been explained by analogy with
cognitive behaviour of higher animals. A re-assessment of the capabilities of the bee is required.
Below the photoreceptors, the next components of the model mechanism are small feature detectors
that are one, two or three ommatidia wide that respond to light intensity, direction of passing
edges or orientation of edges displayed by parameters in the pattern. At the next stage, responses
of the feature detectors for area and edges are summed in various ways in each local region of the
eye to form several types of local internal feature totals, here called cues. The cues are the
units of visual memory in the bee. At the next stage, summation implies that there is one of each
type in each local eye region and that local details of the pattern are lost. Each type of cue has
its own identity, a scalar quantity and a position. The coincidence of the cues in each local
region of the eye is remembered as a retinotopic label for a landmark. Bees learn landmark labels
at large angles to each other and use them to identify a place and find the reward. The receptors,
feature detectors, cues and coincidences of labels for landmarks at different angles, correspond to
a few letters, words and sentences and a summary description for a place. Shapes, objects and
cognitive appraisal of the image have no place in bee vision. Several factors prevented the advance
in understanding until recently. Firstly, until the mid-century, so little was known that no
mechanisms were proposed. At that time it was thought that the mechanism of the visual processing
could be inferred intuitively from a successful training alone or from quantitative observations of
the percentage of correct choices after manipulation of the patterns displayed. The components were
unknown and there were too many unidentified channels of causation in parallel (too many cues
learned at the same time) for this method to succeed. Secondly, for 100 years, the criterion of
success of the bees was their landing at or near the reward hole in the centre of the pattern. At
the moment of choice, therefore, the angle subtended by the pattern at the eye of the bees was very
large, 100-130 deg., with the result that a large part of the eye learned a number of cues and
several labels on the target. As a result, in critical tests the bees would not respond but just
went away, so that the components of the system could not be identified. Much effort was therefore
wasted. These problems were resolved when the size of the target was reduced to about the size of
one or two fields of the cues and landmark labels, 40-45 deg., and the trained bees were tested to
see whether they could or could not recognise the test targets. 10.1242/jeb.030916
Adrian Horridge

|
The Register -
22 hours and 4 minutes ago
Speak Your Brains... we'll translate
The BBC is hosting a "six hour snapshot of a global conversation as it unfolds" today,
simultaneously translating Web2.0rhea contributions into several languages including Chinese,
Arabic and Persian....
Case Study:
WhatsUp keeps Legoland turnstyles ringing
|
BMC Bioinformatics -
1 days and 5 hours ago
Publication Date: 2010 Mar 16 PMID: 20230647Authors: Lee, H. P. - Sheu, T. F. - Tang, C. Y.Journal:
BMC BioinformaticsABSTRACT: BACKGROUND: DNA signatures are distinct short nucleotide sequences that
provide valuable information that is used for various purposes, such as the design of Polymerase
Chain Reaction primers and microarray experiments. Biologists usually use a discovery algorithm to
find unique signatures from DNA databases, and then apply the signatures to microarray experiments.
Such discovery algorithms require to set some input factors, such as signature length l and
mismatch tolerance d, which affect the discovery results. However, suggestions about how to select
proper factor values are rare, especially when an unfamiliar DNA database is used. In most cases,
biologists typically select factor values based on experience, or even by guessing. If the
discovered result is unsatisfactory, biologists change the input factors of the algorithm to obtain
a new result. This process is repeated until a proper result is obtained. Implicit signatures under
the discovery condition (l,d) are defined as the signatures of length = d. A discovery algorithm
that could discover all implicit signatures, such that those that meet the requirements concerning
the results, would be more helpful than one that depends on trial and error. However, existing
discovery algorithms do not address the need to discover all implicit signatures. RESULTS: This
work proposes two discovery algorithms: the consecutive multiple discovery (CMD) algorithm and the
parallel and incremental signature discovery (PISD) algorithm. The PISD algorithm is designed for
efficiently discovering signatures under a certain discovery condition. The algorithm finds new
results by using previously discovered results as candidates, rather than by using the whole
database. The PISD algorithm further increases discovery efficiency by applying parallel computing.
The CMD algorithm is designed to discover implicit signatures efficiently. It uses the PISD
algorithm as a kernel routine to discover implicit signatures efficiently under every feasible
discovery condition. CONCLUSIONS: The proposed algorithms discover implicit signatures efficiently.
The presented CMD algorithm has up to 97% less execution time than typical sequential discovery
algorithms in the discovery of implicit signatures in experiments, when eight processing cores are
used.post to:
CiteULike

|
Nature -
1 days and 5 hours ago
Publication Date: 2010 Mar 14 PMID: 20228792Authors: Chapman, J. A. - Kirkness, E. F. - Simakov, O.
- Hampson, S. E. - Mitros, T. - Weinmaier, T. - Rattei, T. - Balasubramanian, P. G. - Borman, J. -
Busam, D. - Disbennett, K. - Pfannkoch, C. - Sumin, N. - Sutton, G. G. - Viswanathan, L. D. -
Walenz, B. - Goodstein, D. M. - Hellsten, U. - Kawashima, T. - Prochnik, S. E. - Putnam, N. H. -
Shu, S. - Blumberg, B. - Dana, C. E. - Gee, L. - Kibler, D. F. - Law, L. - Lindgens, D. - Martinez,
D. E. - Peng, J. - Wigge, P. A. - Bertulat, B. - Guder, C. - Nakamura, Y. - Ozbek, S. - Watanabe,
H. - Khalturin, K. - Hemmrich, G. - Franke, A. - Augustin, R. - Fraune, S. - Hayakawa, E. -
Hayakawa, S. - Hirose, M. - Hwang, J. S. - Ikeo, K. - Nishimiya-Fujisawa, C. - Ogura, A. -
Takahashi, T. - Steinmetz, P. R. - Zhang, X. - Aufschnaiter, R. - Eder, M. K. - Gorny, A. K. -
Salvenmoser, W. - Heimberg, A. M. - Wheeler, B. M. - Peterson, K. J. - Bottger, A. - Tischler, P. -
Wolf, A. - Gojobori, T. - Remington, K. A. - Strausberg, R. L. - Venter, J. C. - Technau, U. -
Hobmayer, B. - Bosch, T. C. - Holstein, T. W. - Fujisawa, T. - Bode, H. R. - David, C. N. -
Rokhsar, D. S. - Steele, R. E.Journal: NatureThe freshwater cnidarian Hydra was first described in
1702 and has been the object of study for 300 years. Experimental studies of Hydra between 1736 and
1744 culminated in the discovery of asexual reproduction of an animal by budding, the first
description of regeneration in an animal, and successful transplantation of tissue between animals.
Today, Hydra is an important model for studies of axial patterning, stem cell biology and
regeneration. Here we report the genome of Hydra magnipapillata and compare it to the genomes of
the anthozoan Nematostella vectensis and other animals. The Hydra genome has been shaped by bursts
of transposable element expansion, horizontal gene transfer, trans-splicing, and simplification of
gene structure and gene content that parallel simplification of the Hydra life cycle. We also
report the sequence of the genome of a novel bacterium stably associated with H. magnipapillata.
Comparisons of the Hydra genome to the genomes of other animals shed light on the evolution of
epithelia, contractile tissues, developmentally regulated transcription factors, the
Spemann-Mangold organizer, pluripotency genes and the neuromuscular junction.post to:
CiteULike

|
Hack a Day -
1 days and 6 hours ago
Before we get into the how-to, we felt it would be appropriate to explain a little bit about how
this came to be. As many of you may remember, a couple of months ago we attended CES 2010. While there, we also
attended the It Won’t Stay in Vegas Blogger
party and ended up meeting the guys from
Woot. After all of us spent a little bit of time appreciating the open bar, a group of us
stood ended up standing around and talking shop for a while. All of a sudden, a member of our
group, Jeremy Grosser, proposed the idea that Hackaday
and Woot form a partnership. Basically, they would give us a heads up on what they are going to
sell and we would write up a how-to on how to do something cool or useful with that product.
Then, when the day came for Woot to sell the product, we would post our how-to. What you are
reading right now just so happens to be that idea in action, the
first official partnership between Hackaday and Woot. In this how-to, we’ll be taking
apart the Wowwee Rovio mobile webcam robot, adding some super-bright LEDs for better
see-in-the-dark action, and see how some software called RoboRealm can give it a little bit of artificial intelligence.
If don’t have a Rovio yet, you should probably head over to Woot and pick one up so you can follow along. Also, be sure to pick up
a copy of RoboRealm at deals.woot while you’re at it.
It is important to note that while writing this how-to, we used a modified design of the Rovio
Head-Mounted LED hack, posted to RoboCommunity by [Rudolph].
Parts
- 6 super-bright white LEDs (Ours were rated for 3.3v with an intensity of 7000mcd.)
- 1 2N2907 PNP Transistor (We found ours in a 15 transistor combo pack from RadioShack.)
- 1 10ohm resistor
- 1 2.2k ohm resistor
- 22g solid hookup wire
- RadioShack
3×2x1″ Project Enclosure (We used the plastic back panel as a place to mount our
LEDs.)
- 5mm LED holders (Optional. We ended up using them to mount our LEDs in their poorly drilled
holes.)
- Heat-shrink tubing (Optional, but recommended.)
- A small strip of perfboard
We picked up most of our parts from RadioShack, but these parts are so common that you should be
able to pick them up from any electronics components store.
Disassembly
The first step towards giving our Rovio some much needed extra light is, of course, to
disassemble it. After turning the Rovio upside down, remove the six phillips-head screws and
carefully remove the top shell to gain access to the Rovio’s internals. While you
won’t be able to fully detach the top shell, you should be able to lay it next to the
bottom part of the Rovio as seen above.
Inside of the Rovio, there are two main PCBs, the control board and the power supply board. For
the purposes of this how-to, we will only need to modify the power supply board. To gain access
to the power supply board, simply remove the two phillips-head screws that secure the board
vertically. After you gain access to the board, you will then need to identify the ground and
positive pads on the PCB. We will be tapping into these pads later to power our array of LEDs.
One other item of interest to us is the white wire leading from the control board to the LED
headlight board. This wire will allow us to control our new headlights through the Rovio’s
web interface.
After firing up your soldering iron, you’ll need to solder two wires onto the power supply
board. As you can see above, there are two areas with tiny little holes, allowing for easy access
to both GND and VCC. After you have soldered both of these wires, screw the board back in and
then turn your attention towards the white wire mentioned previously. After cutting the white
wire, solder a length of hookup wire to the end of it and insulate it with appropriately sized
heat-shrink tubing. Also, it’s probably a good idea to remove the LED headlight board
entirely. This gives you three openings to run your wires out of from the Rovio to our new
headlight panel. After you’ve removed the board, you can cut the wires leading to both the
infrared LED and receiver. These function as a forward facing “radar” to alert the
user if there are any obstacles ahead. We decided to salvage ours by placing them both in the new
panel that we will soon be creating. If you choose to salvage your infrared “radar”
as well, then remember to solder extension wires between the appropriate leads and the LED and
receiver. We actually used some telephone tap connectors (from RadioShack) to extend the three
wires leading to the infrared receiver, but soldering should work just fine. Now that
you’re finished with all of the internal modifications to the Rovio, we can move on to the
circuitry behind this hack.
The Circuit
In order to make sure that we can control our replacement LED headlights through Rovio’s
web interface, we need to build a circuit that will detect when the headlights are triggered via
the web interface and activate our headlights accordingly. To do this, we’ll use a PNP
transistor to switch the ground of our headlight circuit. As you can see from the schematic
above, the white wire that we mentioned earlier will be connected to the base of the transistor
via a 2.2k resistor, the ground from the power supply board will be connected to the collector of
the transistor, and the emitter of the transistor will be connected to the ground of the parallel
array of LEDs. If you want to, you could probably add a few more LEDs to this design. Just
remember, if you change the number or type of the LEDs, you will have to recalculate the value of
the current-limiting resistor between VCC and the positive pin of the parallel LED array. After
we’ve reviewed our schematic and we’re comfortable with it, we should be ready to
breadboard.
As you can see, there really isn’t that much to our circuit as far as components go. The
black and red wires come directly from the power supply board. Our voltage reading was right
around 6.5v. Please note that your voltage may vary depending on the charge of your Rovio’s
NiMH battery. The green wire was soldered to the white wire inside of the Rovio, and controls
whether the transistor lets the ground flow to the LEDs. We found that the best way to test this
circuit while breadboarding was to turn on the Rovio and turn on and off the headlights using the
web interface. After confirming that the circuit works consistently, you can go ahead and solder
the circuit onto some perfboard and connect to the Rovio.
The circuit really doesn’t take up much space on the perfboard. We decided to use the extra
space on our board as a makeshift terminal block to extend the infrared LED. While soldering the
circuit onto the perfboard, be sure to remember the orientation of your transistor. If you
accidentally put it in backwards, you could switch the collector and emitter, burning out the
transistor. We mention this only because we actually did it the first time we assembled our
board, and we ended up having to swap in a new transistor before reassembling the board. After
you’ve assembled and verified that your circuit works, we can move on to assembling our
headlight panel.
Drilling and Wiring
On your blank panel, carefully drill 8 holes in any configuration you would like. When drilling
your holes, be sure to use a 3/16″ drill bit. While it is actually slightly smaller than a
5mm LED, you can rotate the drill once or twice around to widen the hole. The main thing is that
you don’t want to make the holes too large for the LEDs, which, incidentally, we ended up
doing. One of them was so wide that we had to change the placement of our LEDs to make sure that
they all more or less fit.
I don’t think that I need to get into too much detail here, but the major thing to remember
is that the LEDs need to be wired in parallel. Also, be sure that you are connecting cathode to
cathode and anode to anode, otherwise the whole circuit just won’t work. After you’ve
completely assembled the panel, attach the wires the ground from your perfboard and the VCC from
the power supply board to the circuit, and use the web interface to test that the LEDs get
switched on when they’re supposed to be. If you decided to salvage the infrared
“radar”, don’t forget to attach the infrared LED and receiver to the board in
the two holes left over.
After you’ve finished with the drilling and wiring, you should be ready to attach the panel
to the Rovio. While it was a little tricky for us, we were able to epoxy the panel to the
underside of the front of the Rovio so that it looked like it was vertically mounted.
Now that your Rovio can see better in darker situations, lets take a look at RoboRealm.
RoboRealm
While investigating all of the different things that we could do with our Rovio, we
stumbled upon a piece of software called RoboRealm.
RoboRealm allows you to take video input from any webcam, including the Rovio, and run it through
any number of different modules to process the images. After the images are processed, the
software can even see if any pre-defined conditions are met, and if they are it will instruct the
robot to act accordingly. Combine that visual input with the audio input/output on the Rovio, and
you can do some pretty cool stuff. The interesting part about this software is that it officially supports the Rovio out of the
box. We’ve had a chance to mess around with it a little bit, and as far as we can tell, it
seems like pretty powerful software.
We already know all of the cool things that we want to do with this software and our Rovio, but
we’re curious, what would you do with it? Leave us your answer in the comments, and if we
see something that we find truly inspiring, we’ll do some research, write it up, and post a
how-to explaining how to do it. Who knows, there might even be a brand new Rovio and a free copy
of RoboRealm in it for the winner too…


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Journal of Molecular Biology -
1 days and 10 hours ago
Publication Date: 2010 Mar 11 PMID: 20227420Authors: Lakamper, S. - Thiede, C. - Duselder, A. -
Reiter, S. - Korneev, M. J. - Kapitein, L. C. - Peterman, E. J. - Schmidt, C. F.Journal: J Mol
BiolThe controlled activity of several kinesin motors is required for proper assembly of the
mitotic spindle. Eg5, a homo-tetrameric bipolar Kinesin-5 from Xenopus laevis can cross-link and
slide anti-parallel microtubules apart by a motility mechanism comprising diffusional and
directional motility. It is poorly understood how this mechanism is regulated, possibly by the tail
domains of the opposing motors. In order to explore the basic, unregulated kinesin-5 motor
activity, we generated a stably dimeric Kinesin-5 construct, Eg5Kin, consisting of motor domain and
neck-linker of Eg5 and neck coiled-coil of Drosophila melanogaster Kinesin-1 (DmKHC). In
single-molecule motility assays we found this chimera to be highly processive. In addition, we
studied the effect of the Kinesin-5-specific inhibitor monastrol in single-molecule fluorescence
assays. We found that monastrol reduced the length of processive runs, but, strikingly, did not
affect velocity. Quantitative analysis of the monastrol dose dependence suggests that two bound
monastrol molecules are required to be bound to an Eg5Kin dimer to terminate a run.post to:
CiteULike

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Macworld -
1 days and 13 hours ago
Bundles abound in the Mac world these days. Here's one that brings together ten
applications--including Parallels 5--for a very attractive price.

|
Journal of Molecular Biology -
1 days and 13 hours ago
Publication Date: 2010 Mar 10 PMID: 20226790Authors: Hills, R. D. Jr - Kathuria, S. V. - Wallace,
L. A. - Day, I. J. - Brooks, C. L. 3rd - Matthews, C. R.Journal: J Mol BiolThe thermodynamic
hypothesis of Anfinsen postulates that structures and stabilities of globular proteins are
determined by their amino acid sequences. Chain topology, however, is known to influence the
folding reaction, in that motifs with a preponderance of local interactions typically fold more
rapidly than those with a larger fraction of non-local interactions. Together, the topology and
sequence can modulate the energy landscape and influence the rate at which the protein folds to the
native conformation. To explore the relationship of sequence and topology in the folding of
betaalpha-repeat proteins, which are dominated by local interactions, a combined experimental and
simulation analysis was performed on two members of the flavodoxin-like, alpha/beta/alpha sandwich
fold. Spo0F and the N-terminal receiver domain of NtrC (NT-NtrC) have similar topologies but low
sequence identity, enabling a test of the effects of sequence on folding. Experimental results
demonstrated that both response-regulator proteins fold via parallel channels through highly
structured sub-millisecond intermediates before accessing their cis prolyl peptide bond-containing
native conformations. Global analysis of the experimental results preferentially places these
intermediates off the productive folding pathway. Sequence-sensitive Go-model simulations conclude
that frustration in the folding in Spo0F, corresponding to the appearance of the off-pathway
intermediate, reflects competition for intra-subdomain van der Waals contacts between its N-and
C-terminal subdomains. The extent of transient, premature structure appears to correlate with the
number of isoleucine, leucine and valine (ILV) side-chains that form a large sequence-local cluster
involving the central beta-sheet and helices alpha2, alpha3 and alpha4. The failure to detect the
off-pathway species in the simulations of NT-NtrC may reflect the reduced number of ILV side-chains
in its corresponding hydrophobic cluster. The location of the hydrophobic clusters in the structure
may also be related to the differing functional properties of these response regulators. Comparison
with the results of previous experimental and simulation analyses on the homologous CheY argues
that prematurely-folded unproductive intermediates are a common property of the betaalpha-repeat
motif.post to:
CiteULike

|
Lifehacker -
1 days and 13 hours ago
 If you've
had a tough time choosing between Parallels and VMware Fusion for running Windows on your Mac,
all-things-Apple site MacTech pitted the two virtualization tools against one another in a giant
faceoff. The results: In tests covering boot speed, CPU usage, application performance, CPU speed,
graphics, and more, Parallels 5
came out on top of VMware Fusion 3 in every instance; Parallels particularly outdid VMware in
graphic performance, which you can see demonstrated in the video above. [ MacTech via
Gizmodo]
More »

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