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KillerStartups.com - all -
11 hours and 2 minutes ago
br /In their own wordsbr /br /“We make it really simple to find the driver you need by
indexing all our device driver links by company name and by device type.”br /br /Why it might
be a killerbr /br /It is a practical site that can help you out of trouble in no time at all.br /br
/What it doesbr /br /The NoDevice website is an indexed portal where you can come across a wide
host of drivers, organized both by company and by device type. br brThe featured collection of
drivers takes into account all major manufacturers such as Toshiba, Creative Labs and IBM to name
but three of a collection that spans companies from all over the world. Likewise, the featured
database can be browsed through by device type. Again, there is a very thorough selection to choose
from, and this is presented on the main page alphabetically-organized. These devices range from
mice and keyboards to motherboards and chipsets, and mobile devices of very different denomination
are also featured. br brFurther resources that are part of the NoDevice site include both
downloadable service and user manuals along with driver articles that can be consulted free of
charge. These will let you get the twist on what is going on when it comes to drivers and how to
update your existing setup in the most direct and safe way. br brLastly, if you need a specific
driver that is not featured on the site you can submit a driver request by following the provided
link.br /br /Some questionsbr /br /What platforms are supported? Will more be included as time goes
by?br /br /Link: a href='http://www.nodevice.com'http://www.nodevice.com/abr /Our Review: a
href='http://www.killerstartups.com/Search/nodevice-com-find-drivers-easily'http://www.killerstartups.com/Search/nodevice-com-find-drivers-easily/abr
/br / nbsp;div class="feedflare" a
href="http://feeds.feedburner.com/~f/killerstartups/BkQV?a=49dHM"img
src="http://feeds.feedburner.com/~f/killerstartups/BkQV?i=49dHM" border="0"/img/a a
href="http://feeds.feedburner.com/~f/killerstartups/BkQV?a=Kf6wM"img
src="http://feeds.feedburner.com/~f/killerstartups/BkQV?i=Kf6wM" border="0"/img/a a
href="http://feeds.feedburner.com/~f/killerstartups/BkQV?a=6nJ8m"img
src="http://feeds.feedburner.com/~f/killerstartups/BkQV?i=6nJ8m" border="0"/img/a a
href="http://feeds.feedburner.com/~f/killerstartups/BkQV?a=8VfPm"img
src="http://feeds.feedburner.com/~f/killerstartups/BkQV?i=8VfPm" border="0"/img/a a
href="http://feeds.feedburner.com/~f/killerstartups/BkQV?a=Diq3M"img
src="http://feeds.feedburner.com/~f/killerstartups/BkQV?i=Diq3M" border="0"/img/a a
href="http://feeds.feedburner.com/~f/killerstartups/BkQV?a=0Vzem"img
src="http://feeds.feedburner.com/~f/killerstartups/BkQV?i=0Vzem" border="0"/img/a /divimg
src="http://feeds.feedburner.com/~r/killerstartups/BkQV/~4/413525240" height="1" width="1"/

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Engadget -
11 hours and 32 minutes ago
pFiled under: a href="http://www.engadget.com/category/homeentertainment/" rel="tag"Home
Entertainment/a/pdiv align="center"a
href="http://www.slingcommunity.com/forum/thread/30049/SlingCatcher-Pre-Orders-CAN-IT-BE-TRUE/?page=2#81501"img
vspace="4" hspace="4" border="1" alt=""
src="http://www.blogsmithmedia.com/www.engadget.com/media/2008/10/10-06-08slingcatcher.jpg" //abr
//div After seemingly endless delays, it looks like the a
href="http://engadget.com/tag/slingcatcher"SlingCatcher/a is finally making its way into the world,
as evidenced by this grainy unboxing at the SlingCommunity forums. Sure, it looks exactly the same
as the prepro boxes we've a
href="http://www.engadget.com/2008/01/07/slingcatcher-and-slingmodem-hands-on/"toyed with/a, but we
won't lie -- we've been waiting for this box with breathless anticipation ever since it was a
href="http://www.engadget.com/2007/01/07/sling-medias-new-slingcatcher/"announced/a at CES 2007,
and combined with the recent launch of the Sling 2.0 software, the a
href="http://www.engadget.com/2008/09/25/slingbox-pro-hd-unboxing-and-hands-on/"Slingbox PRO-HD/a,
and the seemingly-imminent launch of the the a
href="http://www.engadget.com/2008/10/03/sling-medias-clip-sling-strides-into-beta-release-looks-immine/"Sling.com
video portal/a, Sling's ending the year strong. Click on for a few more pics, and don't worry --
we'll be blowing this thing out as soon as we get our hands on one.br /br /[Thanks, Christopher]h6
style="clear: both; padding: 8px 0 0 0; height: 2px; font-size: 1px; border: 0; margin: 0; padding:
0;"/h6a
href=http://www.slingcommunity.com/forum/thread/30049/SlingCatcher-Pre-Orders-CAN-IT-BE-TRUE/?page=2#81501Read/anbsp;|nbsp;a
href="http://www.engadget.com/2008/10/07/slingcatcher-gets-unboxed-our-hearts-beat-ever-faster/"
rel="bookmark" title="Permanent link to this entry"Permalink/anbsp;|nbsp;a
href="http://www.engadget.com/forward/1334861/" title="Send this entry to a friend via email"Email
this/anbsp;|nbsp;a
href="http://www.engadget.com/2008/10/07/slingcatcher-gets-unboxed-our-hearts-beat-ever-faster/#comments"
title="View reader comments on this entry"Comments/a pa
href="http://feeds.engadget.com/~a/weblogsinc/engadget?a=mJFzkq"img
src="http://feeds.engadget.com/~a/weblogsinc/engadget?i=mJFzkq" border="0"/img/a/pdiv
class="feedflare" a href="http://feeds.engadget.com/~f/weblogsinc/engadget?a=TDSPm"img
src="http://feeds.engadget.com/~f/weblogsinc/engadget?i=TDSPm" border="0"/img/a a
href="http://feeds.engadget.com/~f/weblogsinc/engadget?a=Ih5em"img
src="http://feeds.engadget.com/~f/weblogsinc/engadget?i=Ih5em" border="0"/img/a /divimg
src="http://feeds.engadget.com/~r/weblogsinc/engadget/~4/413475375" height="1" width="1"/

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PRWeb: Blogging and Social Media -
11 hours and 45 minutes ago
New site presents sales professionals with tools to succeed in a down economy. SalesBook is a Web
2.0 portal for sale professionals and business people to save time, standout and find deals
online. Web briefcase features allow members set up files, load content into public or private
folders, schedule announcements to prospects and network for leads.Basic memberships are free and
allow professionals to be found online when people search for their products and services. (PRWeb
Oct 7, 2008)
Read the full story at http://www.prweb.com/releases/2008/10/prweb1433734.htm
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TechCrunch -
14 hours and 11 minutes ago
Netvibes, the site
that lets users customize their homepages with a variety of widgets, has partnered with Rambler.ru to bring its
widgets to the massive Russian web portal. Rambler is the Yahoo of Russia, with an estimated 40
million users and 3 billion monthly pageviews. The deal is being described as
“multi-year” and worth “multi-millions”, but further details
haven’t been disclosed. Netvibes availability on Rambler.ru is expected to begin in
November.
This marks the first time Netvibes has licensed its platform for installation and distribution to
an independent third party, and probably won’t be the last. In order to stay competitive
with other widget hubs like iGoogle, Netvibes would do well to spur its growth by offering its
widgets to other region-specific portals (that said, Netvibes has been doing well, with a
reported 500 billion widgets served montly). According to the press release, the Rambler homepage
will include Google Search, Blinx video search, and a number of Russian services like Price.ru.
In July Google acquired
Begun, a contextual ad service, from parent company Rambler. As part of the $140 million deal,
Rambler has been using Google for some of its advertising and search functions.
Crunch Network: CrunchBoard
because it’s time for you to find a new Job2.0


|
TIGSource -
14 hours and 38 minutes ago
pimg src="http://farm4.static.flickr.com/3191/2921511680_b2460d48ba_o.png" width="200" height="333"
hspace="10" vspace="5" align="left" alt="Meat Boy" //p pEdmund McMillen and Jonathan McEntee have
finally answered that age-old question: #8220;What would it be like to be one of those slimy meat
patties that came with a href="http://www.x-entertainment.com/articles/0753/"Lunchables/a boxed
lunches?#8221; A masochistic platformer in the vein of a
href="http://www.mattmakesgames.com/games.php"span class="caps"YMM/span/a#8217;s Jumper and FLaiL
series of games, A href="http://www.newgrounds.com/portal/view/463241"Meat Boy/a has you
slippin#8217; and slidin#8217; through 56+ stages to rescue your beloved Band-Aid Girl from the
evil Fetus-in-a-Jar. Absolutely brutal difficulty, with a nice feel to the main character, who is
squishy and slippery./p pIn a world where Veganism is trendy and Garbage Pail Kids are not cool any
more, it#8217;s nice to see guys like Edmund bringing back some good old-fashioned, meaty gross-out
humor, and adding a touch of class to it. A solid game that is rounded out with a sweet score by a
href="http://dbsoundworks.com/"Daniel Baranowsky/a, who also did the music for a
href="http://tigsource.com/articles/2008/09/15/gravity-hook"Gravity Hook/a. If the level editor
were only a bit more user friendly, it#8217;d be tops./p pThe standalone version of the game is
available a href="http://www.newgrounds.com/downloads/flash/meatboy.zip"here/a (13 MB) ./p

|
Engadget -
15 hours and 31 minutes ago
pFiled under: a href="http://www.engadget.com/category/displays/" rel="tag"Displays/a/pdiv
align="center"a
href="http://74.125.93.104/translate_c?hl=enamp;sl=jaamp;u=http://www.mitsubishielectric.co.jp/news/2008/0924.htmamp;prev=/search%3Fq%3DRDT201WDL%26hl%3Den%26safe%3Doff%26client%3Dfirefox-a%26rls%3Dorg.mozilla:en-US:official%26hs%3Dnaramp;usg=ALkJrhiGKrNSEnpLpHDe4oqsqa7jIg7-7w"img
vspace="4" hspace="4" border="0"
src="http://www.blogsmithmedia.com/www.engadget.com/media/2008/10/usb_monitor.jpg" alt="" //abr /
div align="left"Laptop user looking for some dual-display action? Mitsubishi's new a
href="http://www.engadget.com/tag/DisplayLink/"DisplayLink/a-equipped RDT201WDL WIDE LCD is a
20.1-inch wide-format monitor that features a USB hub, built-in Ethernet and WSXGA+ (1,680 x 1,050)
resolution. Energy-conscious consumers will enjoy the on-screen energy meter and three levels of
power usage, and we can all appreciate the fact that this monitor uses up to 36 percent less juice
than a traditional LCD (in addition to the traditional savings DisplayLink provides by skipping the
discrete graphics card). This item is currently available in Japan, and there's no word yet on a
Stateside release date.br /br /[Via a
href="http://www.businesswire.com/portal/site/home/permalink/?ndmViewId=news_viewamp;newsId=20081006005243amp;newsLang=en"Business
Wire/a]br //div /divh6 style="clear: both; padding: 8px 0 0 0; height: 2px; font-size: 1px; border:
0; margin: 0; padding: 0;"/h6a
href=http://74.125.93.104/translate_c?hl=enamp;sl=jaamp;u=http://www.mitsubishielectric.co.jp/news/2008/0924.htmamp;prev=/search%3Fq%3DRDT201WDL%26hl%3Den%26safe%3Doff%26client%3Dfirefox-a%26rls%3Dorg.mozilla:en-US:official%26hs%3Dnaramp;usg=ALkJrhiGKrNSEnpLpHDe4oqsqa7jIgRead/anbsp;|nbsp;a
href="http://www.engadget.com/2008/10/06/mitsubishis-rdt201wdl-displaylink-monitor-now-available/"
rel="bookmark" title="Permanent link to this entry"Permalink/anbsp;|nbsp;a
href="http://www.engadget.com/forward/1334111/" title="Send this entry to a friend via email"Email
this/anbsp;|nbsp;a
href="http://www.engadget.com/2008/10/06/mitsubishis-rdt201wdl-displaylink-monitor-now-available/#comments"
title="View reader comments on this entry"Comments/a pa
href="http://feeds.engadget.com/~a/weblogsinc/engadget?a=NK93Yd"img
src="http://feeds.engadget.com/~a/weblogsinc/engadget?i=NK93Yd" border="0"/img/a/pdiv
class="feedflare" a href="http://feeds.engadget.com/~f/weblogsinc/engadget?a=pBGHm"img
src="http://feeds.engadget.com/~f/weblogsinc/engadget?i=pBGHm" border="0"/img/a a
href="http://feeds.engadget.com/~f/weblogsinc/engadget?a=S67Am"img
src="http://feeds.engadget.com/~f/weblogsinc/engadget?i=S67Am" border="0"/img/a /divimg
src="http://feeds.engadget.com/~r/weblogsinc/engadget/~4/413315227" height="1" width="1"/

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XLR8R News and Features -
20 hours and 29 minutes ago
The 20,000-strong online discussion board, Dubstep
Forum, has announced that it’s closing indefinitely. Over its three-year run, the site,
founded by European producer Dubway, has become a major information portal for dubstep artists,
producers, DJs, radio shows, and intensive, multi-user discussions.
read more
|
Annonces lesjeudis.com -
1 days and 1 hours ago
Societe : IPPON TECHNOLOGIES - Lieu de travail : PARIS ET PROCHE BANLIEUE - Type de contrat : CDI -
Salaire : 40000-5000 - Detail : Aujourd'hui, dans le cadre de notre expansion, et pour le compte de
clients renommés, nous recrutons des EXPERTS J2EE/PORTAILS. Vous intervenez en tant que
spécialiste « Portail J2EE » durant toutes les étapes de
réalisation d'un projet. Qu'il s'agisse d'audit, d'architecture applicative, de conception,
de développement de portlets, mais également de problématiques
d'intégration (Webservices, bus SOA, workflows), nous pouvons faire appel à vos
compétences techniques pour toutes sortes de missions pointues et spécifiques. La
connaissance et la maîtrise d'au moins un portail J2EE est impérative. Ainsi, vos
tâches sont les suivantes: - Conseil ou support au développement - Audit de code ou de
frameworks - Développement et encadrement de développeurs - Optimisation de
l'utilisation de produits d'éditeur Expérience professionnelle souhaitée de 3
ans minimum avec pour connaissances: Architectures : J2EE, SOA, WebServices, XML Portails OSS :
JSR168, Liferay, Jetspeed, Jahia,?. Portails éditeurs : BEA Weblogic Portal, IBM Websphere
Portal, JBoss,? CMS : JackRabbit, Alfresco, Documentum Logiciels : Eclipse, Netbeans, Workshop
Frameworks : Struts, Spring, Hibernate, JSF Serveurs : Tomcat, Websphere, Weblogic, Apache Base de
Données : Oracle, DB2, MySQL Méthode : Merise, UML De formation Bac+5 (type Ecole
d'ingénieurs ou profil universitaire), si vous êtes autonome, rigoureux, curieux et
inventif alors n'hésitez plus une seconde pour nous rejoindre!

|
Manerasdevivir.com -
1 days and 1 hours ago
No te pierdas todos los martes de 17 a 18 horas toda la actualidad del rock y el heavy-metal en
Perol'n'Rock a través de Radio Alaquas (102.7 FM) en la comarca de L'Horta Oest de la
provincia de Valencia o desde la web www.radio.alaquas.org. Además puedes escuchar este
programa en diferido en el portal www.tntradiorock.com (consultar parrilla). Espacio dirigido y
presentado por Jose Bautista, que retorna a la emisora donde debutó radiofonicamente
allá por 1998.
|
KillerStartups.com - all -
1 days and 2 hours ago
Why it might be a killer
It streamlines the process for creating and publishing OPML files.
Some questions
How knowledgeable must you be to use this site? Where can I inform myself about OPML files and
their advantages?
In their own words
“OPML Workstation: Simple, fast, powerful, free.”
What it does
The aptly–titled OPML Workstation website stands as a portal that enables
anybody to create and host OPML files online, within a specific and private work area.
Upon setting your browser to OPMLWorkstation.com, you will be greeted by the main navigation menu.
Both “My Channels” and “Public Channels” boxes are prominently featured,
whereas a “Compose New” heading to the left is joined by a “Special Tools”
banner. The latter includes assorted tools such as a web capture application that enables the user
to make bookmarklets specifically targeted to any of his existing channels. For its part,
PowerPoint presentation can be converted in a more or less instant fashion by following the
“Desktop Presentation Source” link.
Other editing options include a “Upload OPML Source” link and a “RSS feed or
dynamic OPML source” that effectively cover out the different steps that someone in the
process of creating and hosting OPML files will have to deal with sooner or later.
Finally, other sections of the site which can be accessed form the main page include a “My
Profile” page, whereas both “My Team” and a “Member Directory” links
are provided as well for easy access.
Link: http://www.opmlworkstation.com
Our Review: http://www.killerstartups.com/Web-App-Tools/opmlworkstation-com-publish-opml-files-easily


|
AvaxHome - All the news -
1 days and 2 hours ago
Kode9 & the spaceape -
Curious/Portal (2006) MP3 | 320 Kbps | 22 MB Genre : dubstep Featuring one of
Spaceape's most direct verbal performances yet, 'Curious' opens in the wind tunnel - laced by the
lush vocals of new recruit to the Hyperdub Kru, Ms. Haptic - and refrains with the infectiously
ambivalent chorus "Maybe we will save you... Maybe we will kill you". Rushed along by its bustling
hi-hats, 'Curious' drops into Hyperdub's customary wall of sub. While both tracks feature Kode9's
distinctively offkey combination of melodica and synth, and an equally upfront vocal, 'Portal'
swerves into another orbit altogether with deranged, alien synths skewing an accelerated, rollin'
half-step groove, as Spaceape flows from outer to inner space. A wake up call to dub zombies
everywhere.
|
CHIP-Topnews -
1 days and 4 hours ago
Eine Falschmeldung des zu CNN gehörenden Community-News-Portals iReporter.com ließ am
vergangenen Freitag Apples Aktienkurs um gut fünf Prozent an Wert verlieren.  
|
the::unwired -
1 days and 5 hours ago
Telefónica and Facebook have reached a global agreement allowing the integrated
telecommunications operator to seamlessly integrate access to Facebook's mobile service and
applications from all of Telefónica's mobile portals. This agreement will expand the current
relationship between the companies in the UK into a worldwide agreement. Facebook is a leading
social networking website and one of the most visited sites in the world, with more than 100
million registered users. This agreement will enable Telefónica's more than 171 million
mobile subscribers to stay in touch with their friends on Facebook and take part in one or more
social networks, depending on their work, academic, or leisure interests, at any time and from
anywhere.
[Permalink]
(c) 2008 by the::unwired - All Rights Reserved

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DCEmu Forums:: The Homebrew & Gaming Network :: PSP Dreamcast Nintendo DS Wii GP2X Xbox 360 GBA Gamecube PS2 Forums - Dreamcast News Forum -
1 days and 7 hours ago
Issue 23 of 360Zine is now available for free download from GamerZines.com, the portal for free
digital magazines for gamers. It includes an exclusive hands-on preview of Gears of War 2, along
with confirmation of an upcoming digital magazine dedicated to the game.
The issue also has the world's first English screenshots of The Last Remnant from Square Enix,
exclusively available in the magazine's preview and included in an exclusive screensaver available
within the magazine itself.
Continuing the raft of exclusives in the issue, the magazine has an interview with the developers
of Far Cry 2 complete with exclusive screens and two exclusive desktop backgrounds, also available
directly from the magazine page.
It also includes a 19 page supplement for Fable II, and a hands-on preview of WWE Smackdown vs RAW
2009, Saints Row 2 and Guitar Hero: World Tour. There is also a review for Star Wars: The Force
Unleashed and FIFA 09.
Magazine download link is located in credit url.
More...
|
Recent lists on Listible -
1 days and 10 hours ago
Made-from-India.com is not just another B2B portal, but is meant for serious businessman only who
care for Costing, Profit, Turn Over, Brand Promotion, Brand Creation, Brand Make Over, Edge Over
others, and Growth. The key objectives of Made-from-India.com are to construct the largest B2B
trade community. To provide company/business-specific information through an exhaustive trade
directory requiring minimum time for search.
|
PRWeb: Blogging and Social Media -
1 days and 12 hours ago
The Intranet Benchmarking Forum (IBF at www.ibforum.com), an exclusive, confidential intranet and
portal benchmarking group of leading European, US and global organisations, has announced that
Anglo American, Petro Canada, Deutsche Telekom, Abbot and Pfizer have become the latest global
organisations to have joined the forum as corporate members. (PRWeb Oct 6, 2008)
Read the full story at http://www.prweb.com/releases/2008/10/prweb1422134.htm
|
The Code Project Latest Articles -
1 days and 16 hours ago
Step-by-step instructions on how to use the Microsoft Silverlight 1.0 Software Development Kit in
Oracle Weblogic Portal10gR3.
|
DCEmu Forums:: The Homebrew & Gaming Network :: PSP Dreamcast Nintendo DS Wii GP2X Xbox 360 GBA Gamecube PS2 Forums - Dreamcast News Forum -
1 days and 16 hours ago
 If you wanted to, you could by 11 versions of three different NBA games on
Tuesday. Of course, if you wanted to, you could also buy Imagine Fashion Designer New York
and Imagine Babysitters on the same date. And which would be worse? Another jampacked
Tuesday for you, with the big NBA drops, plus Fracture on PS3 and 360, and then
Brothers in Arms: Hell's Highway arrives for the PC if you're waiting on that. Curiosities
include CID The Dummy (Monday, Wii, PC, PSP and PS2) and Crash Bandicoot: Mind Over
Mutant (Tuesday, PS2, DS, Wii, 360). They do not include Etch-a-Sketch or My Spanish Teacher
(both PSP, Tuesday). Full list is on the jump. Let us know what you're
buying/renting/playing/sneering at in the comments.
Monday (Oct. 6)
Nancy Drew: The Haunting of Castle Malloy (PC)
Line Rider 2: Unbound (Wii)
Game Party 2 (Wii)
CID The Dummy (Wii, PC, PSP, PS2)
Tuesday (Oct. 7)
Fracture (PS3, 360)
Brothers in Arms: Hell's Highway (PC)
NBA Live 09 (PSP, PS3, 360, PS2)
NBA 2K9 (PS2, PS3, 360)
NBA Live 09 All-Play (Wii)
NBA 09 The Inside (PSP, PS3, PS2)
Crash Bandicoot: Mind Over Mutant (PS2, DS, Wii, 360)
Disney Sing It (PS3, 360, PC)
Midnight Club: LA Remix (PSP)
My Spanish Coach (PSP)
The Guild 2: Venice (PC)
Ten Pin Alley 2 (Wii)
Spectrobes: Beyond the Portals (DS)
Sniper - Art of Victory (PC)
Six Flags Fun Park (PC, PS2)
Prey the Stars (DS)
Onimusha: The Essentials (PS2)
Kage Densetsu: The Legend of Kage 2 (DS)
Imagine Fashion Designer New York (DS)
Imagine Babysitters (DS)
Guilty Gear 2: Overture (360)
Exodus from the Earth (PC)
Everlight (PC)
Etch A Sketch (PC)
Can You See What I See (PC)
Bleach: Dark Souls (DS)
Army Men: Soldiers of Misfortune (Wii)
Wednesday (Oct. 8)
MLB Stickball (360)
Thursday (Oct. 9)
Supersonic Acrobatic Rocket-Powered Battle-Cars (PS3)
Friday (Oct. 10)
Cake Mania: Baker's Challenge (PS2, PSP)
Source: Gamespot
</img>
</img> </img> </img> </img>
More...

|
Bioinformatics -
1 days and 17 hours ago
Publication Date: 2008 Sep 16 PMID: 18796476br/Authors: Khouangsathiene, S. - Pearson, C. - Street,
S. - Ferguson, B. - Dubay, C.br/Journal: Bioinformaticsbr/br/SUMMARY: MonkeySNP is a web based
resource created by the Genetic Resource and Informatics Program at the Oregon National Primate
Research Center to facilitate access to non-human primate (NHP) SNP data. MonkeySNP is a mirror of
the NCBI dbSNP database and contains additional NHP subpopulation genotype data and visual genotype
displays to support SNP review and selection. AVAILABILITY: http://monkeysnp.ohsu.edu/snp/ CONTACT:
dubayc@ohsu.edu.br/br/post to: a href =
http://www.citeulike.org/posturl?url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Fcmd%3DRetrieve%26db%3DPubMed%26dopt%3DAbstract%26list_uids%3D18796476title=Entrez+PubmedCiteULike/a
|
BMC Bioinformatics -
1 days and 22 hours ago
Publication Date: 2008 Sep 18 PMID: 18801157br/Authors: Tomlinson, C. - Thimma, M. - Alexandrakis,
S. - Castillo, T. - Dennis, J. L. - Brooks, A. - Bradley, T. - Turnbull, C. - Blaveri, E. - Barton,
G. - Chiba, N. - Maratou, K. - Soutter, P. - Aitman, T. - Game, L.br/Journal: BMC
Bioinformaticsbr/br/ABSTRACT: BACKGROUND: Despite considerable efforts within the microarray
community for standardising data format, content and description, microarray technologies present
major challenges in managing, sharing, analysing and re-using the large amount of data generated
locally or internationally. Additionally, it is recognised that inconsistent and low quality
experimental annotation in public data repositories significantly compromises the re-use of
microarray data for meta-analysis. MiMiR, the Microarray data Mining Resource was designed to
tackle some of these limitations and challenges. Here we present new software components and
enhancements to the original infrastructure that increase accessibility, utility and opportunities
for large scale mining of experimental and clinical data. RESULTS: A user friendly Online
Annotation Tool allows researchers to submit detailed experimental information via the web at the
time of data generation rather than at the time of publication. This ensures the easy access and
high accuracy of meta-data collected. Experiments are programmatically built in the MiMiR database
from the submitted information and details are systematically curated and further annotated by a
team of trained annotators using a new Curation and Annotation Tool. Clinical information can be
annotated and coded with a clinical Data Mapping Tool within an appropriate ethical framework.
Users can visualise experimental annotation, assess data quality, download and share data via a
web-based experiment browser called MiMiR Online. All requests to access data in MiMiR are routed
through a sophisticated middleware security layer thereby allowing secure data access and sharing
amongst MiMiR registered users prior to publication. Data in MiMiR can be mined and analysed using
the integrated EMAAS open source analysis web portal or via export of data and meta-data into
Rosetta Resolver data analysis package. CONCLUSIONS: The new MiMiR suite of software enables
systematic and effective capture of extensive experimental and clinical information with the
highest MIAME score, and secure data sharing prior to publication. MiMiR currently contains more
than 150 experiments corresponding to over 3000 hybridisations and supports the Microarray Centre's
large microarray user community and two international consortia. The MiMiR flexible and scalable
hardware and software architecture enables secure warehousing of thousands of datasets, including
clinical studies, from microarray and potentially other -omics technologies.br/br/post to: a href =
http://www.citeulike.org/posturl?url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Fcmd%3DRetrieve%26db%3DPubMed%26dopt%3DAbstract%26list_uids%3D18801157title=Entrez+PubmedCiteULike/a

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